Article
Possible association of NAT2 polymorphism with laryngeal cancer risk: an evidence-based meta-analysis.
Journal of cancer research and clinical oncology - 1 Nov 2011
Ying Xin-Jiang, Dong Pin, Shen Bin, Wang Jie, Wang Sang, Wang Guo
Abstract excerpt
PURPOSE: N-acetyltransferase 2 (NAT2) plays an important role in the metabolism of various potential carcinogens, which can be subdivided into rapid and slow acetylation phenotype according to the different genotypes. A number of studies have been devoted to the association of NAT2 polymorphism with susceptibility to laryngeal carcinoma; however, the results were inconsistent and inconclusive. The aim of the...
Topics
- Arylamine N-Acetyltransferase
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Laryngeal Neoplasms
- Odds Ratio
- Polymorphism, Genetic
- Risk Factors
