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Article

Structural basis of type VI collagen dimer formation.

The Journal of biological chemistry - 25 Apr 2003

Ball Stephen, Bella Jordi, Kielty Cay, Shuttleworth Adrian

Abstract excerpt

We have determined the interactive sites required for dimer formation in type VI collagen. Despite the fact that type VI collagen is a heterotrimer composed of alpha1(VI), alpha2(VI), and alpha3(VI) chains, the formation of dimers is determined principally by interactions of the alpha2(VI) chain. Key components of this interaction are the metal ion-dependent adhesion site (MIDAS) motif of the alpha2C2 A-domain...

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Identifiers

PMID: 12473679
DOI: 10.1074/jbc.M209977200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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