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Article

Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge.

The EMBO journal - 2 Jun 1997

Sasaki T, Mann K, Wiedemann H, Göhring W, Lustig A, Engel J, Chu M L, Timpl R

Abstract excerpt

Fibulin-2 is a novel extracellular matrix protein frequently found in close association with microfibrils containing either fibronectin or fibrillin. The entire protein and its predicted domains were obtained as recombinant products and examined by ultracentrifugation and electron microscopy. This demonstrated a disulfide-linked homodimer of 175 kDa subunits. Partial reduction to monomers identified specifically...

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Identifiers

PMID: 9214621
DOI: 10.1093/emboj/16.11.3035
PMCID: PMC1169922

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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