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Article

Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer.

Breast cancer research : BCR - 1 Jan 2002

Campbell Ian G, Baxter Simon W, Eccles Diana M, Choong David Y H

Abstract excerpt

BACKGROUND: A growing body of evidence suggests that variations in the levels of folate may contribute to the development of cancer. A functional polymorphic variant (C-->T substitution at nucleotide 677) in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene results in the conversion of an alanine to a valine and may modify the risk of breast and other cancers. METHOD: We have investigated the possible...

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Source

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Identifiers

PMID: 12473175
DOI: 10.1186/bcr457
PMCID: PMC137931

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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