Article
[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of breast cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 2004
Qi Jun, Miao Xiao-ping, Tan Wen, Yu Chun-yuan, Liang Gang, Lü Wen-fu, Lin Dong-xin
Abstract excerpt
OBJECTIVE: To investigate the association between genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and risk of breast cancer among women. METHODS: Two hundred seventeen cases with breast cancer and 218 matched controls were genotyped for the MTHFR C677T and A1298C polymorphisms by PCR-RFLP methods. The adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using...
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