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Article

Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR).

Cancer letters - 8 Jul 2002

Sharp L, Little J, Schofield A C, Pavlidou E, Cotton S C, Miedzybrodzka Z, Baird J O C, Haites N E, Heys S D, Grubb D A

Abstract excerpt

Evidence is growing that low folate status may be a factor in the aetiology of several cancers, including breast cancer. The methylenetetrahydrofolate reductase gene (MTHFR), which has a key role in folate metabolism, is polymorphic. We report a case-control study of two functional polymorphisms in MTHFR, dietary folate intake and breast cancer. Sixty-two cases with invasive breast cancer and sixty-six general...

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Source

Identifiers

PMID: 12430180
DOI: 10.1016/s0304-3835(02)00030-7

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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