Article
The methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Asian populations.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Rai Vandana
Abstract excerpt
BACKGROUND: Methylenetetrahydrofolate (MTHFR) is the key enzyme of the folate metabolic pathway and several studies have pointed to association between the MTHFR C677T polymorphism and breast cancer risk. Although significant association was observed in some studies, in others no clear link could be established. OBJECTIVE: A meta-analysis of published Asian case control studies was therefor carried out to shed...
Topics
- Asian People
- Breast
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Odds Ratio
- Polymorphism, Single Nucleotide