Article
The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itself.
The Biochemical journal - 15 Mar 2003
Klomp Adriana E M, Juijn Jenneke A, van der Gun Linda T M, van den Berg Inge E T, Berger Ruud, Klomp Leo W J
Abstract excerpt
We have used indirect immunofluorescense studies and glycosylation-site insertion and deletion mapping to characterize the topology of human copper transporter 1 (hCTR1), the putative human high-affinity copper-import protein. Both approaches indicated that hCTR1 contains three transmembrane domains and that the N-terminus of hCTR1, which contains several putative copper-binding sites, is localized...
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