Article
Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.
Gene - 22 Aug 2000
Lee J, Prohaska J R, Dagenais S L, Glover T W, Thiele D J
Abstract excerpt
A polymerase chain reaction (PCR)-based strategy was used to isolate a mouse cDNA (mCtr1) encoding a Cu transport protein. The deduced mCtr1 protein sequence exhibits 92% identity to human Ctr1, and has structural features in common with known high affinity Cu transporters from yeast. The expression of mouse Ctr1 functionally complements baker's yeast cells defective in high affinity Cu transport....
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