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Article

The ARF-p16 gene locus in carcinogenesis and therapy of head and neck squamous cell carcinoma.

The Laryngoscope - 1 Dec 2002

Yarbrough Wendell G

Abstract excerpt

OBJECTIVES/HYPOTHESIS: We have identified families with a high incidence of tumors including head and neck squamous cell carcinoma (HNSCC). The occurrence of melanoma in these kindreds suggested that the ARF-p16 gene may be involved in carcinogenesis. We wished to determine the gene defect associated with the familial predisposition to HNSCC and to determine whether restoration of the gene may have therapeutic...

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Identifiers

PMID: 12461329
DOI: 10.1097/00005537-200212000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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