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Article

Functional characterization and cellular dynamics of the CDC-42 - RAC - CDC-24 module in Neurospora crassa.

PloS one - 1 Jan 2011

Araujo-Palomares Cynthia L, Richthammer Corinna, Seiler Stephan, Castro-Longoria Ernestina

Abstract excerpt

Rho-type GTPases are key regulators that control eukaryotic cell polarity, but their role in fungal morphogenesis is only beginning to emerge. In this study, we investigate the role of the CDC-42 - RAC - CDC-24 module in Neurospora crassa. rac and cdc-42 deletion mutants are viable, but generate highly compact colonies with severe morphological defects. Double mutants carrying conditional and loss of function...

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Identifiers

PMID: 22087253
DOI: 10.1371/journal.pone.0027148
PMCID: PMC3210136

Genes

CDC42

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional characterization and cellular dynamics of the CDC-42 - RAC - CDC-24 module in Neurospora crassa.PMID 22087253Read ↗

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