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Characterization of outer membrane efflux proteins OpmE, OpmD and OpmB of Pseudomonas aeruginosa: molecular cloning and development of specific antisera.

FEMS microbiology letters - 19 Nov 2002

Murata Takeshi, Gotoh Naomasa, Nishino Takeshi

Abstract excerpt

The third genes, opmE, opmD and opmB, of multidrug efflux operons deduced from the Pseudomonas aeruginosa PAO1 genome data were cloned by polymerase chain reaction. The opmB gene product showed functional cooperation with inner membrane-associated components, MexAB, MexCD and MexXY, of the previously characterized multidrug efflux systems responsible for resistance to antimicrobial agents and extrusion of...

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PMID: 12445646
DOI: 10.1111/j.1574-6968.2002.tb11456.x

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