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Article

Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa.

The Journal of experimental medicine - 1 Jul 2002

Hirakata Yoichi, Srikumar Ramakrishnan, Poole Keith, Gotoh Naomasa, Suematsu Takashi, Kohno Shigeru, Kamihira Shimeru, Hancock Robert E W, Speert David P

Abstract excerpt

Pseudomonas aeruginosa is an important opportunistic human pathogen. Certain strains can transmigrate across epithelial cells, and their invasive phenotype is correlated with capacity to cause invasive human disease and fatal septicemia in mice. Four multidrug efflux systems have been described in P. aeruginosa, however, their contribution to virulence is unclear. To clarify the role of efflux systems in...

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Identifiers

PMID: 12093875
DOI: 10.1084/jem.20020005
PMCID: PMC2194012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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