Aminoglycoside efflux in Pseudomonas aeruginosa: involvement of novel outer membrane proteins.

doi:10.1128/AAC.47.3.1101-1111.2003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Aminoglycoside efflux in Pseudomonas aeruginosa: involvement of novel outer membrane proteins.

Antimicrobial agents and chemotherapy - 1 Mar 2003

Jo James T H, Brinkman Fiona S L, Hancock Robert E W

Abstract excerpt

The expression of tripartite multidrug efflux pumps such as MexA-MexB-OprM in Pseudomonas aeruginosa contributes to intrinsic resistance to a wide variety of antimicrobials, including beta-lactams, chloramphenicol, macrolides, quinolones, and tetracycline. The MexX-MexY linker-pump combination has been shown to be involved in intrinsic resistance to aminoglycosides, but the identity of the cognate outer membrane...

Topics

Aminoglycosides
Anti-Bacterial Agents
Autoradiography
Bacterial Outer Membrane Proteins
DNA, Bacterial
DNA, Complementary
Escherichia coli
Genetic Complementation Test
Membrane Transport Proteins
Microbial Sensitivity Tests
Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 12604548
DOI: 10.1128/AAC.47.3.1101-1111.2003
PMCID: PMC149301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Pseudomonas aeruginosa

RNA, Bacterial

Reverse Transcriptase Polymerase Chain Reaction