Article
Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons.
Biochimica et biophysica acta - 4 Nov 2002
Lindholm Dan, Mercer Eric A, Yu Li Ying, Chen Yuming, Kukkonen Jyrki, Korhonen Laura, Arumäe Urmas
Abstract excerpt
Neuronal apoptosis inhibitory protein (NAIP) has been linked to the inherited disease, spinal muscular atrophy (SMA), which occurs in children with degeneration of the motorneurons. In the nervous system, NAIP is expressed by specific classes of neurons including spinal motorneurons. Recently, NAIP was shown to interact with hippocalcin, which belongs to the neuronal calcium sensor (NCS) protein family. Here we...
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