Article
Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein).
Genomics - 1 Jul 1998
Yaraghi Z, Korneluk R G, MacKenzie A
Abstract excerpt
The spinal muscular atrophies (SMAs), characterized by degeneration of spinal cord motor neurons, are among the most common autosomal recessive disorders. We have previously reported the characterization of an SMA-associated gene designated NAIP (neuronal apoptosis inhibitory protein). This gene,...
Topics
- Animals
- Apoptosis
- Base Sequence
- DNA, Complementary
- Gene Dosage
- Genetic Predisposition to Disease
- Genomic Library
- Legionnaires' Disease
- Mice
- Molecular Sequence Data
- Multigene Family
- Muscular Atrophy, Spinal
- Nerve Tissue Proteins
- Neuronal Apoptosis-Inhibitory Protein
- Restriction Mapping
- Sequence Homology, Nucleic Acid
- Tissue Distribution