Article
Neuronal apoptosis inhibitory protein, NAIP, is an inhibitor of procaspase-9.
The international journal of biochemistry & cell biology - 1 Jun 2010
Davoodi Jamshid, Ghahremani Mohammad-Hossein, Es-Haghi Ali, Mohammad-Gholi Azadeh, Mackenzie Alex
Abstract excerpt
Ability of the full length NAIP and its BIR3 domain in inhibition of the proteases of the intrinsic apoptosis pathway was investigated. Activity of endogenous executioner caspases was drastically reduced by both recombinant NAIP-BIR3 (NBIR3) and the full length protein. Western blotting experimen...
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