Article
Prion protein (PrP) gene polymorphisms associated with natural scrapie cases and their flock-mates in Ireland.
Research in veterinary science - 1 Dec 2002
O'Doherty E, Healy A, Aherne M, Hanrahan J P, Weavers E, Doherty M, Roche J F, Gunn M, Sweeney T
Abstract excerpt
The PrP genotypes associated with natural scrapie in Ireland were determined and a comparison was made between genotypes found in scrapie-infected sheep and those found in healthy animals from scrapie-infected flocks. Seven PrP genotypes were identified in scrapie-infected animals: VV(136)RR(154)QQ(171),VA(136)RR(154)QQ(171),VA(136)RR(154)QR(171),VA(136)RR(154)QH(171),AA(136)RR(154)QQ(171),AA(136)RR(154)QH(171)...
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