Article
Detection of polymorphisms in the prion protein gene in a population of Irish Suffolk sheep.
The Veterinary record - 18 Mar 2000
O'Doherty E, Aherne M, Ennis S, Weavers E, Hunter N, Roche J F, Sweeney T
Abstract excerpt
Natural scrapie is associated with polymorphisms in the prion protein (PrP) gene. In Suffolks, codon 171 is the codon at which most variation is found; RR171 is thought to be associated with resistance to developing the clinical signs of the disease and QQ171 is associated with susceptibility to the disease. The objectives of this study were first to determine the PrP genotypes of Suffolk stock rams in Ireland,...
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