Article
Epidemiological and genetical differences between classical and atypical scrapie cases.
Veterinary research - 1 Jan 2000
Lühken Gesine, Buschmann Anne, Brandt Horst, Eiden Martin, Groschup Martin H, Erhardt Georg
Abstract excerpt
The aim of this study was to analyze the epidemiology and prion protein (PrP) genetics in scrapie-affected sheep flocks in Germany. For this purpose, 224 German scrapie cases in sheep diagnosed between January 2002 and February 2006 were classified as classical or atypical scrapie and the amino acids at codons 136, 141, 154 and 171 were determined. Likewise, representative numbers of flock mates were genotyped....
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