Article
Prion protein gene polymorphisms in pedigree sheep in Ireland.
Research in veterinary science - 1 Feb 2001
O'Doherty E, Aherne M, Ennis S, Weavers E, Roche J F, Sweeney T
Abstract excerpt
The development of clinical signs of scrapie in sheep has been linked to polymorphisms in the prion protein (PrP) gene. The most important polymorphisms appear to be at codons 136, 154 and 171. The objective of this study was to investigate polymorphisms at these codons in five native (Belclare, Galway, Wicklow Cheviot, Donegal Blackface Mountain and Mayo Blackface Mountain) and five imported (Texel, Bleu du...
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