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Article

Presence of clone-specific markers at birth in children with acute lymphoblastic leukaemia.

British journal of cancer - 21 Oct 2002

Hjalgrim L L, Madsen H O, Melbye M, Jørgensen P, Christiansen M, Andersen M T, Pallisgaard N, Hokland P, Clausen N, Ryder L P, Schmiegelow K, Hjalgrim H

Abstract excerpt

Recent studies have suggested that development of childhood acute lymphoblastic leukaemia may often be initiated in utero. To provide further evidence of an prenatal origin of childhood leukaemia, we conducted a molecular biological investigation of nine children with B-precursor acute lymphoblastic leukaemia carrying the chromosomal translocation t(12;21), the most common subtype of all childhood acute...

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Identifiers

PMID: 12434291
DOI: 10.1038/sj.bjc.6600601
PMCID: PMC2364323

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Source receipt: pubmed, retrieved 7 Sept 2026.

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