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Article

Outcome and lineage involvement in t(12;21) childhood acute lymphoblastic leukaemia.

British journal of haematology - 1 May 1997

Lanza C, Volpe G, Basso G, Gottardi E, Barisone E, Spinelli M, Ricotti E, Cilli V, Perfetto F, Madon E, Saglio G

Abstract excerpt

The t(12;21)(p13;q22) translocation has been described recently as the most recurrent genetic lesion in paediatric acute lymphoblastic leukaemias (ALLs). It has also been associated with B-precursor lineage involvement and good outcome. We tested 51 diagnostic paediatric ALLs and found 11 cases with molecular evidence of the t(12;21). Interestingly, amongst t(12;21) positive patients, we report three cases with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9163615
DOI: 10.1046/j.1365-2141.1997.312676.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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