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High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia

15 Apr 2002

Abstract excerpt

The detection of leukemia cells on newborn genetic screening cards ("Guthrie cards") of a small group of patients and several sets of identical twins developing acute lymphoblastic leukemia (ALL) with identical phenotypic and chromosomal markers has provided evidence that childhood ALL cases may arise in utero. We conducted a retrospective study of a randomly selected group of childhood B-precursor ALL patients...

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Share to Acute Lymphoblastic Leukemia research
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PMID: 11929791
DOI: 10.1182/blood.v99.8.2992

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