Alternative models for early onset of childhood leukaemia.

Article

Alternative models for early onset of childhood leukaemia.

The British journal of cancer. Supplement - 1 Aug 1992

Wheldon T E, Mairs R J, Barrett A, Wheldon E G, Gibson B E

Abstract excerpt

This paper considers theoretical models for early-onset childhood leukaemia. The major focus of attention is the two-hit mutational model. A simple mathematical representation is used to explore mechanisms which might lead to onset of leukaemia at an unusually early age. Two such mechanisms are c...

Topics

Cell Division
Cell Transformation, Neoplastic
Humans
Infant
Kinetics
Leukemia
Models, Genetic
Models, Theoretical
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.