Article
G-protein beta-3-subunit and eNOS gene polymorphism in transplant recipients with long-term renal graft function.
Kidney & blood pressure research - 1 Jan 2002
Viklický Ondrej, Hubácek Jaroslav A, Vítko Stefan, Heemann Uwe W, Vasarhelyi Barna, Kohnle Mathias, Teplan Vladimir, Lácha Jirí, Szabó Attila J
Abstract excerpt
BACKGROUND: Despite new immunosuppressive drugs, only a minority of graft survive over 15 years. The aim of our study was to determine the influence of gene polymorphisms in the G-protein-beta(3) subunit (Gbeta3) and endothelial nitric oxide synthase (eNOS) on the long-term outcome of kidney grafts. METHODS: Using PCR, corresponding genotypes in Gbeta3 (C825T) and eNOS (G894T) gene polymorphism were evaluated in...
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