Article
Endothelial nitric oxide synthase polymorphism influences renal allograft outcome.
Clinical transplantation - 1 Feb 2014
Uyar Murathan, Sezer Siren, Ozdemir Fatma Nurhan, Kulah Eyup, Arat Zubeyde, Atac Fatma Belgin, Haberal Mehmet
Abstract excerpt
BACKGROUND: Atherosclerotic lesions within the graft are considered to be a major cause of interstitial fibrosis/tubular atrophy (IF/TA). We evaluated the factors that influence the development of IF/TA and three- and five-yr graft survival including nitric oxide synthase (eNOS) and angiotensin II type 1 and type 2 receptor gene polymorphism. METHODS: Seventy-one male and 35 female patients (age: 34.9 ± 11.2 yr)...
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