Article
The impact of eNOS, MTR and MTHFR polymorphisms on renal graft survival in children and young adults.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2009
Artifoni Lina, Benetti Elisa, Centi Sonia, Negrisolo Susanna, Ghiggeri Gian Marco, Ginevri Fabrizio, Ghio Luciana, Edefonti Alberto, Brambilla Caterina, Cagni Nicoletta, Murer Luisa
Abstract excerpt
BACKGROUND: The main cause of reduced long-term graft survival is chronic allograft injury. Cardiovascular risk factors such as hyperhomocysteinaemia, accumulation of asymmetric dimethylarginine, increased oxidative stress and decreased production of nitric oxide seem to play an important role. F...
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