Article
Effect of antisense human telomerase RNA on malignant phenotypes of gastric carcinoma.
Journal of gastroenterology and hepatology - 1 Nov 2002
Yang Shi-Ming, Fang Dian-Chun, Yang Jin-Liang, Liang Guang-Ping, Lu Rong, Luo Yuan-Hui, Liu Wei-Wen
Abstract excerpt
AIM: The study was designed to explore the effects of antisense human telomerase RNA (ahTR) on the malignant phenotype of gastric carcinoma cell line SGC-7901, and its potential role in gene therapy for tumors. METHODS: An ahTR eukaryotic expression vector, including the sequence of template region of telomere repeats, was constructed by recombinant technology of molecules and then transfected into gastric...
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