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Article

Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jun 2008

Yang Shi-Ming, Fang Dian-Chun, Yang Jin-Liang, Chen Ling, Luo Yuan-Hui, Liang Guang-Ping

Abstract excerpt

Telomerase activity is detected in more than 90% of examined tumors but not in most normal somatic cells. Among three subunits of human telomerase, human telomerase reverse transcriptase (hTERT) is the rate-limiting component for telomerase activity. Therefore, targeting hTERT represents a promising approach for diminishing telomerase function that will probably not cause substantial side effects on telomerase...

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PMID: 18414191
DOI: 10.1097/CEJ.0b013e3282b71f0d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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