Article
[Reversion of the malignant phenotype of gastric cancer by c-erbB-2 specific ribozyme].
Zhonghua yi xue za zhi - 1 Apr 1999
Bi F, Zhang X, Hui H
Abstract excerpt
OBJECTIVE: To probe the effect of c-erbB-2 specific ribozyme to the malignant phenotype of gastric cancer. METHODS: The eucaryotic expression vector of c-erbB-2 specific ribozyme RZ1 was designed by computer and named pDOR-RZ1. The transfection of the gastric cancer cell line SGC-7901 was mediated by Lipofect AMINE. Flow cytometry was used to analyse the expression of the c-erbB-2 product P185. In vivo study of...
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