Article
[Alteration of the malignant phenotype of human hepatocellular carcinoma cell line Hep3B by specially synthesized oligodeoxynucleotides].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 May 2005
Li Yan, Liu Yin-kun, Shen Yue-fang, Sun Rui-xia
Abstract excerpt
OBJECTIVES: To study the inhibitory effect of specially synthesized oligodeoxynucleotide (SODN) on malignant phenotype of human hepatocellular carcinoma Hep3B cells by complementary binding to the fourth promoter of IGF-2 gene. METHODS: A SODN was synthesized according to the sequence of the fourth promoter of IGF-2 gene, and was then transfected into Hep3B cells which overexpressed IGF-2. IGF-2 gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
