Article
Methylenetetrahydrofolate Reductase gene polymorphism in patients receiving hemodialysis.
Bosnian journal of basic medical sciences - 1 Apr 2010
Kiseljaković Emina, Resić Halima, Kapur Lejla, Hasić Sabaheta, Jadrić Radivoj
Abstract excerpt
Methylenetetrahydrofolate Reductase (MTHFR) is key enzyme in metabolism of homocysteine. Homozygotes for mutation (TT genotype) have hyperhomocysteinemia, risk factor for atherosclerosis development. The aim of the study was to find out distribution of genotype frequencies of C677T MTHFR among patients on maintenance hemodialysis. Possible association of alleles and genotypes of C677T polymorphism of the MTHFR...
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