Article
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Nephron - 1 Mar 2001
Lim P S, Hung W R, Wei Y H
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) gene polymorphism has been shown to be associated with cardiovascular disease in healthy subjects as well as in patients with end-stage renal disease (ESRD). In this study, we examined the allelic frequency and genotype distribution of the MTHFR gen...
Topics
- Adult
- Aged
- Alleles
- Carotid Artery Diseases
- Case-Control Studies
- Cross-Sectional Studies
- Female
- Gene Frequency
- Genotype
- Homocysteine
- Humans
- Kidney Failure, Chronic
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Oxidoreductases Acting on CH-NH Group Donors
- Point Mutation
- Polymorphism, Genetic