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Localisation of human DNA polymerase κ to replication foci

14 Nov 2002

Abstract excerpt

The replication of the undamaged genomic DNA requires error-free DNA polymerases delta and epsilon as part of a protein complex that acts continuously along the double helix. In contrast, when the genomic structure is perturbed, DNA replication needs to function more flexibly to bypass DNA distortions. It has been proposed that the newly discovered error prone DNA polymerases play a role in the replication of...

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PMID: 12414988
DOI: 10.1242/jcs.00162

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