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Article

Isolation of living neurons from human elderly brains using the immunomagnetic sorting DNA-linker system.

The American journal of pathology - 1 Nov 2002

Konishi Yoshihiro, Lindholm Kristina, Yang Li-Bang, Li Rena, Shen Yong

Abstract excerpt

Isolation and culture of mature neurons from affected brain regions during diseased states provide a well-suited in vitro model system to study age-related neurodegeneration under dynamic conditions at cellular levels. We have developed a novel technique to isolate living neurons from rapidly autopsied human elderly brains, and have succeeded in keeping them alive in vitro. Specifically, the parietal cortex...

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Identifiers

PMID: 12414505
DOI: 10.1016/S0002-9440(10)64435-5
PMCID: PMC1850778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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