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Article

Synaptic glutamate receptor clustering in mice lacking the SH3 and GK domains of SAP97.

The European journal of neuroscience - 1 Oct 2002

Klöcker Nikolaj, Bunn Robert C, Schnell Eric, Caruana Georgina, Bernstein Alan, Nicoll Roger A, Bredt David S

Abstract excerpt

Postsynaptic targeting of the Drosophila tumour suppressor discs-large (Dlg) critically depends on its SH3 and GK domains. Here, we asked whether these domains are also involved in subcellular targeting of the mammalian Dlg homolog SAP97 and its interacting partners in CNS cortical neurons by analysing a recently described mouse mutant lacking the SH3 and GK domains of SAP97. Both wildtype and truncated SAP97...

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Source

Identifiers

PMID: 12405965
DOI: 10.1046/j.1460-9568.2002.02228.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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