Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATM mutations in sporadic lymphoid tumours.

Leukemia & lymphoma - 1 Aug 2002

Stankovic T, Stewart G S, Byrd P, Fegan C, Moss P A H, Taylor A M R

Abstract excerpt

Patients with the autosomal recessive disorder ataxia telangiectasia (A-T) show the biallelic inactivation of the ataxia telangiectasia mutated (ATM) gene. A-T patients exhibit a predisposition to the development of a wide range of lymphoid tumours, suggesting that the ATM protein normally plays an important role in the prevention of both T and B cell malignancies. The ATM protein is a 370 kDa protein kinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Cell Cycle Proteins
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Leukemia, T-Cell

Share to Lymphoma, Mantle-Cell

Share to Protein Serine-Threonine Kinases

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 12400598
DOI: 10.1080/1042819021000002884

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATM mutations in sporadic lymphoid tumours.PMID 12400598Read ↗

ATM gene and lymphoid malignancies.Semantic proximity Read ↗

Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia.Semantic proximity Read ↗

The ataxia telangiectasia gene in familial and sporadic cancer.Semantic proximity Read ↗

Ataxia telangiectasia gene mutations in leukaemia and lymphoma.Semantic proximity Read ↗

Inactivation of the ATM Gene in T-Cell Prolymphocytic LeukemiasSemantic proximity Read ↗

Inactivation of the ATM gene in T-cell prolymphocytic leukemias.Semantic proximity Read ↗

Somatic ATM Mutations Indicate a Pathogenic Role of ATM in B-Cell Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Biallelic mutations in the ATM gene in T-prolymphocytic leukemia.Semantic proximity Read ↗

Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

ATM mutations are rare in familial chronic lymphocytic leukemia.Semantic proximity Read ↗

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia.Semantic proximity Read ↗

Germ-line ATM gene alterations are associated with susceptibility to sporadic T-cell acute lymphoblastic leukemia in children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.