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In Candida albicans, White-Opaque Switchers Are Homozygous for Mating Type

1 Oct 2002

Abstract excerpt

The relationship between the configuration of the mating type locus (MTL) and white-opaque switching in Candida albicans has been examined. Seven genetically unrelated clinical isolates selected for their capacity to undergo the white-opaque transition all proved to be homozygous at the MTL locus, either MTLa or MTLalpha. In an analysis of the allelism of 220 clinical isolates representing the five major clades...

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PMID: 12399384
DOI: 10.1093/genetics/162.2.737

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