Article
Mating-type locus homozygosis, phenotypic switching and mating: a unique sequence of dependencies in Candida albicans.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jan 2004
Soll David R
Abstract excerpt
A small proportion of clinical strains of Candida albicans undergo white-opaque switching. Until recently it was not clear why, since most strains carry the genes differentially expressed in the unique opaque phase. The answer to this enigma lies in the mating process. The majority of C. albicans strains are heterozygous for the mating type locus MTL (a/alpha) and cannot undergo white-opaque switching. However,...
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