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Article

White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating.

Cell - 9 Aug 2002

Miller Mathew G, Johnson Alexander D

Abstract excerpt

Discovered over a decade ago, white-opaque switching in the human fungal pathogen Candida albicans is an alternation between two quasistable, heritable transcriptional states. Here, we show that white-opaque switching and sexual mating are both controlled by mating type locus homeodomain proteins and that opaque cells mate approximately 10(6) times more efficiently than do white cells. These results show that...

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Identifiers

PMID: 12176317
DOI: 10.1016/s0092-8674(02)00837-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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