Article
<i>In Silico</i> Genomic Analysis of the Human and Murine Guanylate-Binding Protein (GBP) Gene Clusters
1 May 2006
Abstract excerpt
The guanylate-binding proteins (GBPs) were among the first interferon (IFN)-stimulated genes (ISGs) discovered, but until recently, little was known about their functions and even less about the composition of the gene family. Analysis of the promoter of human GBP-1 contributed significantly toward the understanding of Jak-Stat signaling and the delineation of the IFN-gamma activation site (GAS) and...
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