Article

The proinflammatory role of guanylate binding protein 5 in inflammatory bowel diseases

2022-03-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>NLRP3 inflammasome is implicated in the pathogenesis of inflammatory bowel diseases (IBD). Since guanylate binding protein 5 (GBP5) induces the NLRP3 inflammasome activity, we aim to investigate the potential role of GBP5 in IBD pathogenesis. <bold>Results: </bold>The expression of GBP5, NLRP3 inflammasome and related cytokines and chemokines were examined in tw...

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Literature Corpus work: 7cd1741f-a429-5946-8404-071124b23730
DOI: 10.21203/rs.3.rs-1421081/v1

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