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Article

Deletions within the mouse beta-globin locus control region preferentially reduce beta(min) globin gene expression.

Genomics - 1 Feb 2000

Alami R, Bender M A, Feng Y Q, Fiering S N, Hug B A, Ley T J, Groudine M, Bouhassira E E

Abstract excerpt

The mouse beta-globin gene cluster is regulated, at least in part, by a locus control region (LCR) composed of several developmentally stable DNase I hypersensitive sites located upstream of the genes. In this report, we examine the level of expression of the beta(min) and beta(maj) genes in adult mice in which HS2, HS3, or HS5,6 has been either deleted or replaced by a selectable marker via homologous...

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Identifiers

PMID: 10704289
DOI: 10.1006/geno.1999.6104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletions within the mouse beta-globin locus control region preferentially reduce beta(min) globin gene expression.PMID 10704289Read ↗

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