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Article

A reverse genetics approach for recovery of recombinant influenza B viruses entirely from cDNA.

Journal of virology - 1 Nov 2002

Jackson David, Cadman Andrew, Zurcher Thomas, Barclay Wendy S

Abstract excerpt

The recovery of recombinant influenza A virus entirely from cDNA was recently described (9, 19). We adapted the technique for engineering influenza B virus and generated a mutant bearing an amino acid change E116G in the viral neuraminidase which was resistant in vitro to the neuraminidase inhibitor zanamivir. The method also facilitates rapid isolation of single-gene reassortants suitable as vaccine seeds and...

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Identifiers

PMID: 12388735
DOI: 10.1128/jvi.76.22.11744-11747.2002
PMCID: PMC136801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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