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Molecular studies of influenza B virus in the reverse genetics era

6 Oct 2010

Abstract excerpt

Recovery of an infectious virus of defined genetic structure entirely from cDNA and the deduction of information about the virus resulting from phenotypic characterization of the mutant is the process of reverse genetics. This approach has been possible for a number of negative-strand RNA viruses since the recovery of rabies virus in 1994. However, the recovery of recombinant orthomyxoviruses posed a greater...

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PMID: 20926635
DOI: 10.1099/vir.0.026187-0

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