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Article

Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action.

American journal of physiology. Endocrinology and metabolism - 1 Jan 2003

Sadow Peter M, Chassande Olivier, Gauthier Karine, Samarut Jacques, Xu Jianming, O'Malley Bert W, Weiss Roy E

Abstract excerpt

Isoforms of the thyroid hormone receptor (TR)alpha and TRbeta genes mediate thyroid hormone action. How TR isoforms modulate tissue-specific thyroid hormone (TH) action remains largely unknown. The steroid receptor coactivator-1 (SRC-1) is among a group of transcriptional coactivator proteins that bind to TRs, along with other members of the nuclear receptor superfamily, and modulate the activity of genes...

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Share to Nuclear Receptor Coactivator 1
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Source

Identifiers

PMID: 12388168
DOI: 10.1152/ajpendo.00226.2002

Genes

SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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