Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac expression and function of thyroid hormone receptor beta and its PV mutant.

Endocrinology - 1 Nov 2003

Swanson Eric A, Gloss Bernd, Belke Darrell D, Kaneshige Masahiro, Cheng Sheue-Yann, Dillmann Wolfgang H

Abstract excerpt

Thyroid hormone (T3) influences cardiac function, and mice with deletion of thyroid hormone receptor (TR)alpha have diminished cardiac function. TR alpha 1 represents 70% and TR beta 1 represents the remaining 30% of TR in ventricular myocytes, and its role in cardiac function is not well established. To determine the role of TR beta 1 in detail, we compared contractility in isolated perfused hearts from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium-Transporting ATPases
Share to Cyclic Nucleotide-Gated Cation Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

Share to Propylthiouracil

Share to Sarcoplasmic Reticulum Calcium-Transporting ATPases

Share to Thyroid Hormone Receptors alpha

Share to Thyroid Hormone Receptors beta

Share to Triiodothyronine

Source

Identifiers

PMID: 12959993
DOI: 10.1210/en.2003-0522

Genes

HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac expression and function of thyroid hormone receptor beta and its PV mutant.PMID 12959993Read ↗

Cardiac dysfunction caused by myocardium-specific expression of a mutant thyroid hormone receptor.Semantic proximity Read ↗

Impaired Ca2+ handling and contraction in cardiomyocytes from mice with a dominant negative thyroid hormone receptor alpha1.Semantic proximity Read ↗

The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice.Semantic proximity Read ↗

Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy.Semantic proximity Read ↗

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.Semantic proximity Read ↗

Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family.Semantic proximity Read ↗

Thyroid Hormone-Regulated Cardiac Gene Expression and Cardiovascular DiseaseSemantic proximity Read ↗

Cardiovascular phenotype and temperature control in mice lacking thyroid hormone receptor-beta or both alpha1 and beta.Semantic proximity Read ↗

A novel contractile phenotype with cardiac transgenic expression of the human P2X4 receptor.Semantic proximity Read ↗

Marked potentiation of the dominant negative action of a mutant thyroid hormone receptor beta in mice by the ablation of one wild-type beta allele.Semantic proximity Read ↗

Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction.Semantic proximity Read ↗

Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.