Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules.

Developmental biology - 1 Feb 2013

Griffin John N, Compagnucci Claudia, Hu Diane, Fish Jennifer, Klein Ophir, Marcucio Ralph, Depew Michael J

Abstract excerpt

Craniofacial development requires an exquisitely timed and positioned cross-talk between the embryonic cephalic epithelia and mesenchyme. This cross-talk underlies the precise translation of patterning processes and information into distinct, appropriate skeletal morphologies. The molecular and cellular dialogue includes communication via secreted signaling molecules, including Fgf8, and effectors of their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Ectoderm
Share to Eye

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

Share to Gene Expression Regulation, Developmental

Share to In Situ Nick-End Labeling

Share to Microscopy, Electron, Scanning

Share to Nasal Mucosa

Source

Open in PubMed Open full text

Identifiers

PMID: 23201021
DOI: 10.1016/j.ydbio.2012.11.014
PMCID: PMC4086262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules.PMID 23201021Read ↗

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.Semantic proximity Read ↗

Increased FGF8 signaling promotes chondrogenic rather than osteogenic development in the embryonic skull.Semantic proximity Read ↗

The genetic basis of normal and abnormal craniofacial development.Semantic proximity Read ↗

Detailed analysis of chick optic fissure closure reveals Netrin-1 as an essential and conserved mediator of epithelial fusion during vertebrate embryogenesisSemantic proximity Read ↗

Distinct requirements for <i>wnt9a</i> and <i>irf6</i> in extension and integration mechanisms during zebrafish palate morphogenesisSemantic proximity Read ↗

FGF signalling in craniofacial development and developmental disorders.Semantic proximity Read ↗

Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice.Semantic proximity Read ↗

Fibroblast growth factor signaling in cranial suture development and pathogenesis.Semantic proximity Read ↗

FGF signaling through FGFR1 is required for olfactory bulb morphogenesis.Semantic proximity Read ↗

FGF signaling in craniofacial biological control and pathological craniofacial development.Semantic proximity Read ↗

Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning.Semantic proximity Read ↗

Genetics of craniofacial development and malformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.