Article
Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.
Genomics - 15 Apr 2001
Sood R, Bonner T I, Makalowska I, Stephan D A, Robbins C M, Connors T D, Morgenbesser S D, Su K, Faruque M U, Pinkett H, Graham C, Baxevanis A D, Klinger K W, Landes G M, Trent J M, Carpten J D
Abstract excerpt
The aim of this study was to develop a saturated transcript map of the region encompassing the HPC1 locus to identify the susceptibility genes involved in hereditary prostate cancer (OMIM 176807) and hyperparathyroidism-jaw tumor syndrome (OMIM 145001). We previously reported the generation of a 6-Mb BAC/PAC contig of the candidate region and employed various strategies, such as database searching, exon-trapping,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.